Mast Cell Activation Syndrome
Mast Cell Activation Syndrome (MCAS) is a condition where mast cells, a type of blood cell, become overactive and release chemicals inappropriately. Mast cells normally help protect the body from infection and injury, but in MCAS they can be triggered too easily, or without a clear cause.
This release of chemicals can affect many systems in the body, leading to a wide range of symptoms which can present as allergic-type reactions such as hives, flushing, swelling, stomach pain, diarrhoea, headaches, and fatigue. Many people experience severe reactions, including some with anaphylaxis, which can be life-threatening.
Triggers vary widely and can include foods, medications, temperature changes, stress, and fragrances amongst others. Because symptoms overlap with many other conditions and affect each person differently, MCAS can be difficult to recognise and diagnose. With treatment, which often involves medication, diet, and lifestyle changes, many people are able to manage their symptoms and improve their quality of life.
Support
For people who have, or think they may have, MCAS
Getting a diagnosis and treatment
Help with managing MCAS
If you have a loved-one with MCAS
If you are a looking for support:
For Healthcare Professionals
For additional information or support, please get in touch info@mastcellaction.org
Mast Cell Action
Mast Cell Action exists to improve the lives of people affected by Mast Cell Activation Syndrome (MCAS). Our vision is of a world where everyone affected by Mast Cell Disease has their symptoms acknowledged and experiences listened to, to achieve a correct diagnosis, and to receive the care and support that they need.
At Mast Cell Action, we believe in the power of community, the strength of passion, and the boundless potential of collective action. We support people with MCAS through advocacy, information, and by building a compassionate community of understanding and support.